• Structural studies of serotonin receptor family

    Structures of all 12 G-protein coupled serotonin receptors. Cryo-EM maps of (A) 5-HT1 family: aripiprazole bound 5-HT1A (PDB ID: 7E2Z), donitriptan bound 5-HT1B (PDB ID: 6G79), 5-HT bound 5-HT1D (PDB ID: 7E32), BRL-54443 bound 5-HT1E (PDB ID: 7E33), Lasmiditan bound 5-HT1F (PDB ID: 7EXD), (B) 5-HT2 family: 25-CN-NBOH bound 5-HT2A (PDB ID: 6WHA), LSD bound 5-HT2B (PDB ID: 7SRR), LSD bound 5-HT2B in complex with β-arrestin (PDB ID: 7SRS), Lorcaserin bound 5-HT2C (PDB ID: 8DPI) and (C) 5-HT4/5/6/7 family: 5-HT bound 5-HT4 (PDB ID: 7XT8), 5-CT bound 5-HT5 (PDB ID: 7UM5), 5-HT bound 5-HT6 (PDB ID: 7XTB), and 5-CT bound 5-HT7 (PDB ID: 7XTC).
  • Longevity through diet restriction and immunity

    DR effects in animals. DR prevents age-related diseases in various tissues including brain, heart, and muscle in animals and humans. Furthermore, DR increases the lifespan of animals. An impact of DR on longevity has not yet been confirmed in humans.

BMB Reports 2023; 56(10): 527~574
Invited Mini Reviews
Structural studies of serotonin receptor family
Apeksha Parajulee & Kuglae Kim
BMB Reports 2023; 56(10): 527-536  https://doi.org/10.5483/BMBRep.2023-0147
Longevity through diet restriction and immunity
Jeong-Hoon Hahm , Hyo-Deok Seo , Chang Hwa Jung & Jiyun Ahn
BMB Reports 2023; 56(10): 537-544  https://doi.org/10.5483/BMBRep.2023-0095
Articles
Boeravinone B, a natural rotenoid, inhibits osteoclast differentiation through modulating NF-κB, MAPK and PI3K/Akt signaling pathways
Xianyu Piao , Jung-Woo Kim , Moonjung Hyun, Zhao Wang, Suk-Gyun Park, In A Cho, Je-Hwang Ryu , Bin-Na Lee , Ju Han Song & Jeong-Tae Koh
BMB Reports 2023; 56(10): 545-550  https://doi.org/10.5483/BMBRep.2023-0054
Ginsenoside Rg2 inhibits osteoclastogenesis by downregulating the NFATc1, c-Fos, and MAPK pathways
Sung-Hoon Lee, Shin-Young Park , Jung Ha Kim, Nacksung Kim & Junwon Lee
BMB Reports 2023; 56(10): 551-556  https://doi.org/10.5483/BMBRep.2023-0100
Tumor suppressor Parkin induces p53-mediated cell cycle arrest in human lung and colorectal cancer cells
Byung Chul Jung , Sung Hoon Kim , Yoonjung Cho & Yoon Suk Kim
BMB Reports 2023; 56(10): 557-562  https://doi.org/10.5483/BMBRep.2023-0134
Epigenetic insights into colorectal cancer: comprehensive genome-wide DNA methylation profiling of 294 patients in Korea
Soobok Joe , Jinyong Kim, Jin-Young Lee , Jongbum Jeon , Iksu Byeon, Sae-Won Han, Seung-Bum Ryoo , Kyu Joo Park , Sang-Hyun Song, Sheehyun Cho , Hyeran Shim, Hoang Bao Khanh Chu, Jisun Kang , Hong Seok Lee, DongWoo Kim, Young-Joon Kim , Tae-You Kim & Seon-Young Kim
BMB Reports 2023; 56(10): 563-568  https://doi.org/10.5483/BMBRep.2023-0096
Deciphering the DNA methylation landscape of colorectal cancer in a Korean cohort
Seok-Byung Lim, Soobok Joe , Hyo-Ju Kim, Jong Lyul Lee, In Ja Park, Yong Sik Yoon, Chan Wook Kim, Jong-Hwan Kim , Sangok Kim, Jin-Young Lee , Hyeran Shim, Hoang Bao Khanh Chu, Sheehyun Cho , Jisun Kang , Si-Cho Kim , Hong Seok Lee, Young-Joon Kim , Seon-Young Kim & Chang Sik Yu
BMB Reports 2023; 56(10): 569-574  https://doi.org/10.5483/BMBRep.2023-0106

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October 2023
Volume 56
Issue 10

2022 SCI Impact Factor 3.8

BIOCHEMISTRY & MOLECULAR BIOLOGY 134/285

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