• Stromal cells and epigenetics: emerging key players of chronic inflammatory skin diseases

    Heterogeneity of stromal cells in chronic inflammatory disease. Subpopulations of stromal cells, including fibroblasts, blood vascular endothelial cells (BECs), and lymphatic endothelial cells (LECs), identified from single-cell transcriptomics, display specific molecular repatterning, potentially leading to activated states. Activated stromal cells can trigger cytokine/chemokine responses, enhance T-cell persistence, and alter extracellular matrix (ECM) components relevant to the pathogenesis of chronic inflammatory skin diseases.
  • Fluorescence-based techniques for investigating estrogen receptor dynamics

    Schematic overview of fluorescence-based techniques for ER signaling dynamics. This figure offers a visual representation of the use of fluorescence-based approaches in studying the five principal estrogen receptor (ER) signaling pathways. Each pathway is outlined within a pink frame and features an array of techniques for exploring ER dynamics. Notable methods demonstrated include fluorescent protein tagging (FPt), fluorescence resonance energy transfer (FRET), bioluminescence resonance energy transfer (BRET), and proximity ligation assay (PLA). Additionally, the involvement of 17β-estradiol (E2) in these assays is highlighted.

BMB Reports 2024; 57(11): 465~508
Invited Mini Reviews
Stromal cells and epigenetics: emerging key players of chronic inflammatory skin diseases
Jihye Kim & Michael Detmar
BMB Reports 2024; 57(11): 465-471  https://doi.org/10.5483/BMBRep.2024-0039
Fluorescence-based techniques for investigating estrogen receptor dynamics
Kiseok Han, Gyuho Choi & Tae-Jin Kim
BMB Reports 2024; 57(11): 472-483  https://doi.org/10.5483/BMBRep.2024-0091
Articles
Characterization of an orthotopic mouse transplant model reveals early changes in the tumor microenvironment of lung cancer
Minsu Na , Huiram Kang , Nayoung Kim , Areum Jo & Hae-Ock Lee
BMB Reports 2024; 57(11): 484-489  https://doi.org/10.5483/BMBRep.2024-0015
Specialized pro-resolving mediator 7S MaR1 inhibits IL-6 expression via modulating ROS/p38/ERK/NF-κB pathways in PM10-exposed keratinocytes
Jinju Kim , Hyo-Min Park , Chae-Min Lim , Kyeong-Bae Jeon , Seonhwa Kim , Jin Lee, Jin-Tae Hong , Deok-Kun Oh , Young Yang & Do-Young Yoon
BMB Reports 2024; 57(11): 490-496  https://doi.org/10.5483/BMBRep.2024-0124
Differential roles of N- and C-terminal LIR motifs in the catalytic activity and membrane targeting of RavZ and ATG4B proteins
Sang-Won Park , Ju-Hui Park, Haneul Choi, Pureum Jeon, Seung-Hwan Lee, Won-Dong Shin, Hun-Joo Kim, Jin-A Lee & Deok-Jin Jang
BMB Reports 2024; 57(11): 497-502  https://doi.org/10.5483/BMBRep.2024-0084
Antisense-mediated splicing correction as a therapeutic approach for p53 K120R mutation

Doyeong Kim, Sang-Min Park, Seo-Young Lee, Jinchul Kim, Han-Byul Jung, Young Sook Kim & Sun-Ku Chung

BMB Reports 2024; 57(11): 503-508  https://doi.org/10.5483/BMBRep.2024-0118

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Current Issue

November 2024
Volume 57
Issue 11

2023 SCI Impact Factor 2.9

BIOCHEMISTRY & MOLECULAR BIOLOGY 178/313

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