BMB Reports 2021; 54(8): 437-437  https://doi.org/10.5483/BMBRep.2021.54.8.267
Erratum to: Common and differential effects of docosahexaenoic acid and eicosapentaenoic acid on helper T-cell responses and associated pathways
Jaeho Lee1,# , Yu Ri Choi1,# , Miso Kim1 , Jung Mi Park2 , Moonjong Kang2 , Jaewon Oh3 , Chan Joo Lee3 , Sungha Park3 , Seok-Min Kang3 , Ichiro Manabe4 , Soo-jin Ann5,* & Sang-Hak Lee3,*
1Graduate Program of Science for Aging, Yonsei University, Seoul 03722, 2Department of Biostatistics and Computing, Graduate School of Yonsei University, Seoul 03722, 3Division of Cardiology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 03722, Korea, 4Department of Disease Biology and Molecular Medicine, Chiba University Graduate School of Medicine, Chiba 260-8670, Japan, 5Integrative Research Center for Cerebrovascular and Cardiovascular Diseases, Yonsei University College of Medicine, Seoul 03722, Korea
Correspondence to: Sang-Hak Lee, Tel: +82-2-2228-8460; Fax: +82-2-2227-7732; E-mail: shl1106@yuhs.ac; Soo-jin Ann, Tel: +82-2-2228-8460; Fax: +82-2-2227-7732; E-mail: hoppum@yuhs.ac
#These authors contributed equally to this work.
Received: August 4, 2021; Published online: August 31, 2021.
© Korean Society for Biochemistry and Molecular Biology. All rights reserved.

cc This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract

In the originally published version of this article, there was an error in the Supplementary information. Fig. 1 as following image was missing in the Supplementary Information. The Supplementary file in the original version has now been updated to include the corrected. We apologize for any inconvenience that this may have caused.

Erratum to: BMB Reports 2021; 54(5): 278-283, PMID: 33972011

Keywords: Adaptive immunity, Atherosclerosis, Co-culture technique, Interleukin, Unsaturated fatty acids
Body

In the originally published version of this article, there was an error in the Supplementary information. Fig. 1 as following image was missing in the Supplementary Information. The Supplementary file in the original version has now been updated to include the corrected. We apologize for any inconvenience that this may have caused.

Figure
Supplementary Fig. 1. Genes and pathways of Th1 cells affected by DHA and EPA. Naïve CD4+ T cells were co-cultured with BMDCs with or without DHA or EPA. After purification, cDNA was obtained from rRNA-depleted total RNA and microarray was performed. Heat map diagram of mRNAs expressed by DHA or EPA-treated CD4+ T cells compared to control (A and D). The color scale in the map illustrates the relative expression level of mRNAs: red and green indicate above and below the average, respectively. To validate the microarray results of DHA treatment, independent qPCRs were used to assess the expression of Tiam1, Efna5, Igf1, Prkacb, Gng2, Grin1, Vegfa, and β-actin (B). To validate the microarray results of EPA treatment, independent qPCRs were used to assess the expression of Cpt1a, Runx2, Vegfa, Itga2, Slc27a2, and β-actin (E). Graphs of upregulated and downregulated genes were located upper and lower parts, respectively. Gene ontology (GO) term enrichment analysis was presented. The GO annotation was based on 260 and 160 DEGs by DHA and EPA, respectively. The vertical and horizontal axes represent the GO category and −log of P value, respectively (C and F). To verify the roles of Igf1 and Cpt1a in Th1 cell differentiation, flow cytometric analyses were performed after transfection with Igf1 siRNA or etomoxir and treatment with DHA or EPA (G). The qPCR was conducted with technical duplicates, and the data shown represent three independent replicates. *P < 0.05; **P < 0.01 compared with the control group. C: control; ns: not significant.


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