DEGs and GO-BP enrichment analysis using scRNA-seq. (A) Number of DEGs (with a minimum 1.3-fold change, adjusted P-value < 0.05) and enriched GO-BP terms (adjusted P-value < 0.05) in each cluster compared to other clusters. (B, C) Enriched GO-BP terms for upregulated genes in cluster 1 (vs others) and downregulated genes in clusters 0 (vs others) and 2 (vs others). (D) Enriched GO-BP terms for upregulated genes in cluster 3 (vs clusters 0 and 2) and downregulated genes in clusters 0 (vs others) and 2 (vs cluster 3). (E) Enriched GO-BP terms for downregulated genes in cluster 3 (vs others) and upregulated genes in clusters 0 (vs cluster 3) and 2 (vs cluster 3).