Suppression of adipocyte differentiation by C1-27. (A) The cytotoxic effect of C1-27 under cell proliferating (black bars) and differentiating conditions (white bars). (B) The chemical structure of C1-27 (upper), and its effect on adipocyte differentiation as determined by cellular lipid staining (lower). (C, D) Expressions of adipogenic marker genes at the indicated incubation times after induction and the effect of 7 μM C1-27.
