Histological examination and analysis. (A) Representative H&E-stained liver tissue sections. Bar, 20 μm. The open arrowheads indicate the central vein and filled arrowheads indicate steatosis. The asterisks indicate lobular inflammation foci. The arrows indicate hepatocyte ballooning. (B) Total histological score, (C) steatosis, (D) lobular inflammation, and (E) hepatocyte ballooning were exhibited. The results are shown as the mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001.