Signaling transduction instigated by the Golgi complex. (Left) Palmitoylation of Ras obtained at the Golgi complex is required for membrane recruitment and activation of signaling pathways. Signaling pathway of N-Ras at the Golgi complex shows a sustained activity as compared to N-Ras signaling instigated from the plasma membrane. (Right) Retrograde COPI transport is regulated by KDELR-mediated PKA signaling pathway. Cargo export in TGN is regulated by SRC signaling pathway which is activated by KDELR.
