Exogenous leptin induces muscle resistance to dexamethasone (Dex). (A) The expression of proteins in the gastrocnemius muscle of WT mice with or without leptin treatment. Leptin (5 μg/g) was administered i.p. 45 min before sample collection (n = 3). Changes in muscle weight (B, n = 8) and protein expression (C, n = 3) in the muscle after 7 days of Dex (25 mg/kg/day) and/or leptin (5 μg/g/day) treatment. *P < 0.05 compared to WT mice without any treatment. #P < 0.05 compared to dexamethasone-treated WT mice. Data represent the mean ± SEM.