Effects of PEP-1-FK506BP on cell proliferation. WT9-7 cells were treated with PEP-1-FK506BP (5 μM) and rapamycin (0.5 nM). After 24 h, the expression levels of Akt (A), p70S6K and mTOR (B), and ERK (C) were determined by Western blotting using the indicated specific antibodies. **P < 0.01, compared with control cells.