BMB Reports : eISSN 1976-670X

Cited by CrossRef (120)

  1. Zhipeng Tao, Xu Wu. Transcription Factor Regulatory Networks. .
    https://doi.org/10.1007/978-1-0716-2815-7_9
  2. M.A.E. Silva, A.L.M. Brand, F.J.M. Novaes, C.M Rezende. Cafestol, Kahweol and Their Acylated Derivatives: Antitumor Potential, Pharmacokinetics, and Chemopreventive Profile. Food Reviews International 2022:1
    https://doi.org/10.1080/87559129.2022.2141776
  3. Arij Fouzat, Ola Jihad Hussein, Ishita Gupta, Halema F. Al-Farsi, Ashraf Khalil, Ala-Eddin Al Moustafa. Elaeagnus angustifolia Plant Extract Induces Apoptosis via P53 and Signal Transducer and Activator of Transcription 3 Signaling Pathways in Triple-Negative Breast Cancer Cells. Front. Nutr. 2022;9
    https://doi.org/10.3389/fnut.2022.871667
  4. Thu-Huyen Pham, Hyo-Min Park, Jinju Kim, Jin Tae Hong, Do-Young Yoon. STAT3 and p53: Dual Target for Cancer Therapy. Biomedicines 2020;8:637
    https://doi.org/10.3390/biomedicines8120637
  5. Srimathi Devi Jegannathan, Santhosh Arul, Haripriya Dayalan. Zerumbone Sensitizes the Anti-Cancer Efficacy of Cisplatin in Hepatocellular Carcinoma Cells. ACAMC 2022;22:2885
    https://doi.org/10.2174/1871520622666220324090801
  6. Attalla F. El-kott, Eman R. ElBealy, Ali S. Alshehri, Ayman E. El-Kenawy, Heba S. Khalifa, Amira M. AlRamlawy. Salidroside induces cell apoptosis and inhibits the invasiveness of HT29 colorectal cells by regulating protein kinase R, NF-κB and STAT3. CBM 2021;31:13
    https://doi.org/10.3233/CBM-203257
  7. Juan Li, De Bi, Xin Zhang, Yunpeng Cao, Kun Lv, Lan Jiang. Network Pharmacology and Inflammatory Microenvironment Strategy Approach to Finding the Potential Target of Siraitia grosvenorii (Luo Han Guo) for Glioblastoma. Front. Genet. 2021;12
    https://doi.org/10.3389/fgene.2021.799799
  8. Svetlana Gaponova, Olga Patutina, Aleksandra Sen’kova, Ekaterina Burakova, Innokenty Savin, Andrey Markov, Elena Shmendel, Mikhail Maslov, Dmitry Stetsenko, Valentin Vlassov, Marina Zenkova. Single Shot vs. Cocktail: A Comparison of Mono- and Combinative Application of miRNA-Targeted Mesyl Oligonucleotides for Efficient Antitumor Therapy. Cancers 2022;14:4396
    https://doi.org/10.3390/cancers14184396
  9. Mamta Kumari, Praveen Thaggikuppe Krishnamurthy, Piyong Sola. Targeted Drug Therapy to Overcome Chemoresistance in Triple-negative Breast Cancer. CCDT 2020;20:559
    https://doi.org/10.2174/1568009620666200506110850
  10. Radosveta Gencheva, Elias S.J. Arnér. Thioredoxin Reductase Inhibition for Cancer Therapy. Annu. Rev. Pharmacol. Toxicol. 2022;62:177
    https://doi.org/10.1146/annurev-pharmtox-052220-102509
  11. Lei Fan, Jingtao Ru, Tao Liu, Chao Ma. Identification of a Novel Prognostic Gene Signature From the Immune Cell Infiltration Landscape of Osteosarcoma. Front. Cell Dev. Biol. 2021;9
    https://doi.org/10.3389/fcell.2021.718624
  12. Jiao Liu, Kailin Jiao, Qian Zhou, Jun Yang, Keke Yang, Chunyan Hu, Ming Zhou, Zhong Li, Jayeeta Ghose. Resveratrol Alleviates 27-Hydroxycholesterol-Induced Senescence in Nerve Cells and Affects Zebrafish Locomotor Behavior via Activation of SIRT1-Mediated STAT3 Signaling. Oxidative Medicine and Cellular Longevity 2021;2021:1
    https://doi.org/10.1155/2021/6673343
  13. Hyungjin Kim, Hyo-Jung Lee, Deok Yong Sim, Ji Eon Park, Chi-Hoon Ahn, Su-Yeon Park, Eungyeong Jang, Bonglee Kim, Sung-Hoon Kim. The Antitumor Effect of Cinnamaldehyde Derivative CB-PIC in Hepatocellular Carcinoma Cells via Inhibition of Pyruvate and STAT3 Signaling. IJMS 2022;23:6461
    https://doi.org/10.3390/ijms23126461
  14. Li‐Bin Gao, Xin‐Le Zhu, Jing‐Xian Shi, Ling Yang, Zhen‐Qiang Xu, Song‐Lin Shi. HnRNPA2B1 promotes the proliferation of breast cancer MCF‐7 cells via the STAT3 pathway. J Cell Biochem 2021;122:472
    https://doi.org/10.1002/jcb.29875
  15. Anibal Méndez‑Clemente, Alejandro Bravo‑Cuellar, Salvador González‑Ochoa, Maria Santiago‑Mercado, Luis Palafox‑Mariscal, Luis Jave‑Suárez, Fabiola Solorzano‑Ibarra, Maria Villaseñor‑García, Pablo Ortiz‑Lazareno, Georgina Hernández‑Flores. Dual STAT‑3 and IL‑6R inhibition with stattic and tocilizumab decreases migration, invasion and proliferation of prostate cancer cells by targeting the IL‑6/IL‑6R/STAT‑3 axis. Oncol Rep 2022;48
    https://doi.org/10.3892/or.2022.8349
  16. Zhong Wu, Jin Zhou, Xiaoyang Zhang, Zhouwei Zhang, Yingtian Xie, Jie bin Liu, Zandra V. Ho, Arpit Panda, Xintao Qiu, Paloma Cejas, Israel Cañadas, Fahire Goknur Akarca, James M. McFarland, Ankur K. Nagaraja, Louisa B. Goss, Nikolas Kesten, Longlong Si, Klothilda Lim, Yanli Liu, Yanxi Zhang, Ji Yeon Baek, Yang Liu, Deepa T. Patil, Jonathan P. Katz, Josephine Hai, Chunyang Bao, Matthew Stachler, Jun Qi, Jeffrey J. Ishizuka, Hiroshi Nakagawa, Anil K. Rustgi, Kwok-Kin Wong, Matthew Meyerson, David A. Barbie, Myles Brown, Henry Long, Adam J. Bass. Reprogramming of the esophageal squamous carcinoma epigenome by SOX2 promotes ADAR1 dependence. Nat Genet 2021;53:881
    https://doi.org/10.1038/s41588-021-00859-2
  17. Carole A. Daly, Martine J. Smit, Bianca Plouffe. The constitutive activity of the viral-encoded G protein-coupled receptor US28 supports a complex signalling network contributing to cancer development. 2020;48:1493
    https://doi.org/10.1042/BST20190988
  18. Simona Moravcová, Eva Filipovská, Veronika Spišská, Irena Svobodová, Jiří Novotný, Zdeňka Bendová. The Circadian Rhythms of STAT3 in the Rat Pineal Gland and Its Involvement in Arylalkylamine-N-Acetyltransferase Regulation. Life 2021;11:1105
    https://doi.org/10.3390/life11101105
  19. Nafiseh Behranvand, Farzad Nasri, Reza Zolfaghari Emameh, Pouria Khani, Asieh Hosseini, Johan Garssen, Reza Falak. Chemotherapy: a double-edged sword in cancer treatment. Cancer Immunol Immunother 2022;71:507
    https://doi.org/10.1007/s00262-021-03013-3
  20. Sabrina Giantulli, Elisabetta Tortorella, Francesco Brasili, Susanna Scarpa, Barbara Cerroni, Gaio Paradossi, Angelico Bedini, Stefania Morrone, Ida Silvestri, Fabio Domenici. Effect of 1-MHz ultrasound on the proinflammatory interleukin-6 secretion in human keratinocytes. Sci Rep 2021;11
    https://doi.org/10.1038/s41598-021-98141-2
  21. Salman Ahmed, Hamed Mirzaei, Michael Aschner, Ajmal Khan, Ahmed Al-Harrasi, Haroon Khan. Marine peptides in breast cancer: Therapeutic and mechanistic understanding. Biomedicine & Pharmacotherapy 2021;142:112038
    https://doi.org/10.1016/j.biopha.2021.112038
  22. Huanyuan Wang, Dexin Peng, Mei Gan, Zhisheng He, Yukang Kuang. CPEB3 overexpression caused by miR-106b-5p inhibition inhibits esophageal carcinoma in-vitro progression and metastasis. 2022;33:335
    https://doi.org/10.1097/CAD.0000000000001265
  23. In-Hyoung Yang, Seung-Hyun Hong, Minjung Jung, Chi-Hyun Ahn, Hye-Jung Yoon, Seong Doo Hong, Sung-Dae Cho, Ji-Ae Shin. Cryptotanshinone chemosensitivity potentiation by TW-37 in human oral cancer cell lines by targeting STAT3–Mcl-1 signaling. Cancer Cell Int 2020;20
    https://doi.org/10.1186/s12935-020-01495-2
  24. Lei Hua, Yaqing Zhou, Can Hou, Jiaxin Chen, Yanjun Wang, Sheng Zhang, Hanxiao Zhou, Shu He, Enzhi Jia. Shexiang Baoxin Pills Inhibited Proliferation and Migration of Human Coronary Artery Smooth Muscle Cells via PI3K/AKT/mTOR Pathway. Front. Cardiovasc. Med. 2021;8
    https://doi.org/10.3389/fcvm.2021.700630
  25. Manal Alfwuaires, Hany Elsawy, Azza Sedky. Acacetin Inhibits Cell Proliferation and Induces Apoptosis in Human Hepatocellular Carcinoma Cell Lines. Molecules 2022;27:5361
    https://doi.org/10.3390/molecules27175361
  26. Melani Luque, Marta Sanz-Álvarez, Andrea Santamaría, Sandra Zazo, Ion Cristóbal, Lorena de la Fuente, Pablo Mínguez, Pilar Eroles, Ana Rovira, Joan Albanell, Juan Madoz-Gúrpide, Federico Rojo. Targeted Therapy Modulates the Secretome of Cancer-Associated Fibroblasts to Induce Resistance in HER2-Positive Breast Cancer. IJMS 2021;22:13297
    https://doi.org/10.3390/ijms222413297
  27. Hsueh-Yao Chu, Yin-Ju Chen, Chun-Jieh Hsu, Yang-Wei Liu, Jeng-Fong Chiou, Long-Sheng Lu, Fan-Gang Tseng. Physical Cues in the Microenvironment Regulate Stemness-Dependent Homing of Breast Cancer Cells. Cancers 2020;12:2176
    https://doi.org/10.3390/cancers12082176
  28. Stefano Comità, Saveria Femmino, Cecilia Thairi, Giuseppe Alloatti, Kerstin Boengler, Pasquale Pagliaro, Claudia Penna. Regulation of STAT3 and its role in cardioprotection by conditioning: focus on non-genomic roles targeting mitochondrial function. Basic Res Cardiol 2021;116
    https://doi.org/10.1007/s00395-021-00898-0
  29. Sung-Jun Hong, Jin-Tae Kim, Su-Jung Kim, Nam-Chul Cho, Kyeojin Kim, Seungbeom Lee, Young-Ger Suh, Kyung-Cho Cho, Kwang Pyo Kim, Young-Joon Surh. An Electrophilic Deguelin Analogue Inhibits STAT3 Signaling in H-Ras-Transformed Human Mammary Epithelial Cells: The Cysteine 259 Residue as a Potential Target. Biomedicines 2020;8:407
    https://doi.org/10.3390/biomedicines8100407
  30. Chien-Chi Lu, Hsiao-Chi Tsai, Dong-Ying Yang, Shih-Wei Wang, Ming-Hsui Tsai, Chun-Hung Hua, Kwei-Jing Chen, Michael Yuan-Chien Chen, Ming-Yu Lien, Chih-Hsin Tang. The Chemokine CCL4 Stimulates Angiopoietin-2 Expression and Angiogenesis via the MEK/ERK/STAT3 Pathway in Oral Squamous Cell Carcinoma. Biomedicines 2022;10:1612
    https://doi.org/10.3390/biomedicines10071612
  31. Junbiao Wang, Romilde Iannarelli, Stefania Pucciarelli, Emiliano Laudadio, Roberta Galeazzi, Mara Giangrossi, Maurizio Falconi, Lishan Cui, Aleix Marti Navia, Michela Buccioni, Gabriella Marucci, Daniele Tomassoni, Laura Serini, Stefania Sut, Filippo Maggi, Stefano Dall’Acqua, Cristina Marchini, Augusto Amici. Acetylshikonin isolated from Lithospermum erythrorhizon roots inhibits dihydrofolate reductase and hampers autochthonous mammary carcinogenesis in Δ16HER2 transgenic mice. Pharmacological Research 2020;161:105123
    https://doi.org/10.1016/j.phrs.2020.105123
  32. Mohammad Dabaghi, Seyed Mohammad Mahdi Rasa, Emilio Cirri, Alessandro Ori, Francesco Neri, Rainer Quaas, Ingrid Hilger. Iron Oxide Nanoparticles Carrying 5-Fluorouracil in Combination with Magnetic Hyperthermia Induce Thrombogenic Collagen Fibers, Cellular Stress, and Immune Responses in Heterotopic Human Colon Cancer in Mice. Pharmaceutics 2021;13:1625
    https://doi.org/10.3390/pharmaceutics13101625
  33. Ngoc Bao To, Yen Thi-Kim Nguyen, Jeong Yong Moon, Meran Keshawa Ediriweera, Somi Kim Cho. Pentadecanoic Acid, an Odd-Chain Fatty Acid, Suppresses the Stemness of MCF-7/SC Human Breast Cancer Stem-Like Cells through JAK2/STAT3 Signaling. Nutrients 2020;12:1663
    https://doi.org/10.3390/nu12061663
  34. Israa Cheikh, Chirine El-Baba, Ali Youssef, Najat Saliba, Akram Ghantous, Nadine Darwiche. Lessons learned from the discovery and development of the sesquiterpene lactones in cancer therapy and prevention. Expert Opinion on Drug Discovery 2022
    https://doi.org/10.1080/17460441.2023.2147920
  35. Haosheng Ni, Hui Sun, Miaosen Zheng, Tingting Bian, Jian Liu, Xiaoli Li, Jianguo Zhang, Yifei Liu. Mining database for the expression and clinical significance of STAT family in head and neck squamous cell carcinomas. Translational Oncology 2021;14:100976
    https://doi.org/10.1016/j.tranon.2020.100976
  36. Laura Magnano, Andrea Rivero, Estella Matutes. Large Granular Lymphocytic Leukemia: Current State of Diagnosis, Pathogenesis and Treatment. Curr Oncol Rep 2022;24:633
    https://doi.org/10.1007/s11912-021-01159-y
  37. Jin Li, Zi-Hui Wang, Ya-Min Dang, Dan-Ni Li, Zhen Liu, Da-Peng Dai, Jian-Ping Cai. MTH1 suppression enhances the stemness of MCF7 through upregulation of STAT3. Free Radical Biology and Medicine 2022;188:447
    https://doi.org/10.1016/j.freeradbiomed.2022.06.240
  38. Fanglin Niu, Yi Yu, Zhuozhuo Li, Yuanyuan Ren, Zi Li, Qiang Ye, Ping Liu, Chenshuang Ji, Lu Qian, Yuyan Xiong. Arginase: An emerging and promising therapeutic target for cancer treatment. Biomedicine & Pharmacotherapy 2022;149:112840
    https://doi.org/10.1016/j.biopha.2022.112840
  39. Shokoofe Noori, Mitra Nourbakhsh, Shabnam Farzaneh, Afshin Zarghi. A Ferrocene Derivative Reduces Cisplatin Resistance in Breast Cancer Cells through Suppression of MDR-1 Expression and Modulation of JAK2/STAT3 Signaling Pathway. ACAMC 2020;20:2285
    https://doi.org/10.2174/1871520620666200807103903
  40. Shu Dai, Cheng Wang, XingTao Zhao, Cheng Ma, Ke Fu, Yanfang Liu, Cheng Peng, Yunxia Li. Cucurbitacin B: A review of its pharmacology, toxicity, and pharmacokinetics. Pharmacological Research 2023;187:106587
    https://doi.org/10.1016/j.phrs.2022.106587
  41. Lara J. Bou Malhab, Wael M. Abdel-Rahman. Obesity and Inflammation: Colorectal Cancer Engines. CMP 2022;15:620
    https://doi.org/10.2174/1874467214666210906122054
  42. Dong Hyun Jo, Seungbeom Lee, Eunoo Bak, Chang Sik Cho, Young Taek Han, Kyeojin Kim, Young-Ger Suh, Jeong Hun Kim. Antitumor Activity of Novel Signal Transducer and Activator of Transcription 3 Inhibitors on Retinoblastoma. Mol Pharmacol 2021;100:63
    https://doi.org/10.1124/molpharm.120.000231
  43. Wenbo Shao, Cunxin Zhang, Kang Li, Ziang Lu, Zihao Zhao, Kai Gao, Chaoliang Lv. Wogonin inhibits inflammation and apoptosis through STAT3 signal pathway to promote the recovery of spinal cord injury. Brain Research 2022;1782:147843
    https://doi.org/10.1016/j.brainres.2022.147843
  44. Shiqi Kong, Xinbo Ge, Xin Li, Zhenbo Liu, Rui Zhang, Ming Yang, Zhenhai Wang, Zhenzhong Li. SD‐36 promotes growth inhibition and induces apoptosis via suppression of Mcl‐1 in glioma. J Cell Mol Med 2021;25:8261
    https://doi.org/10.1111/jcmm.16754
  45. Byung-Hak Kim, Haeri Lee, Cheol Gyu Park, Ae Jin Jeong, Song-Hee Lee, Kum Hee Noh, Jong Bae Park, Chung-Gi Lee, Sun Ha Paek, Hyunggee Kim, Sang-Kyu Ye. STAT3 Inhibitor ODZ10117 Suppresses Glioblastoma Malignancy and Prolongs Survival in a Glioblastoma Xenograft Model. Cells 2020;9:722
    https://doi.org/10.3390/cells9030722
  46. Josephine Hendrikson, Ying Liu, Wai Har Ng, Jing Yi Lee, Abner Herbert Lim, Jui Wan Loh, Cedric C.Y. Ng, Whee Sze Ong, Joey Wee-Shan Tan, Qiu Xuan Tan, Gillian Ng, Nicholas B. Shannon, Weng Khong Lim, Tony K.H. Lim, Clarinda Chua, Jolene Si Min Wong, Grace Hwei Ching Tan, Jimmy Bok Yan So, Khay Guan Yeoh, Bin Tean Teh, Claramae Shulyn Chia, Khee Chee Soo, Oi Lian Kon, Iain Beehuat Tan, Jason Yongsheng Chan, Melissa Ching Ching Teo, Chin-Ann J. Ong. Ligand-mediated PAI-1 inhibition in a mouse model of peritoneal carcinomatosis. Cell Reports Medicine 2022;3:100526
    https://doi.org/10.1016/j.xcrm.2022.100526
  47. Banumathi, Ankith Sherapura, Vikas H. Malojirao, Zabiulla, B. S. Sharath, Prabhu Thirusangu, Riaz Mahmood, N. Suchetha Kumari, Shrinath M. Baliga, Shaukath Ara Khanum, B. T. Prabhakar. Antiproliferative pharmacophore azo-hydrazone analogue BT-1F exerts death signalling pathway targeting STAT3 in solid tumour. Pharmacol. Rep 2022;74:353
    https://doi.org/10.1007/s43440-021-00345-w
  48. Joaquín Martínez‑López, Pau Montesinos, Nieves López‑Muñoz, Rosa Ayala, Pilar Martínez‑Sánchez, Julian Gorrochategui, José Rojas‑Rudilla, Daniel Primo, Juan-Miguel Bergua‑Burgues, María Calbacho, Evelyn Acuña‑Cruz, José Pérez‑Simón, Adolfo De La Fuente, Jaime Pérez De Oteyza, Rebeca Rodriguez‑Veiga, José Pina, Blanca Boluda, Isabel Cano, María Paciello Coronel, Juan Ballesteros. Biomarker‑driven phase Ib clinical trial of OPB‑111077 in acute myeloid leukemia. Med Int 2022;2
    https://doi.org/10.3892/mi.2022.32
  49. Chun-Yan Li, Chun-Ya Chen, Jian-Hong An, Jian-Bin Wu, Hong Shen. Normal Basal Epithelial Cells Stimulate the Migration and Invasion of Prostate Cancer Cell RM-1 by TGF-β1/STAT3 Axis in vitro. CMAR 2021;Volume 13:3685
    https://doi.org/10.2147/CMAR.S303122
  50. Rosa K. Kortekaas, Janette K. Burgess, Roël van Orsoy, David Lamb, Megan Webster, Reinoud Gosens. Therapeutic Targeting of IL-11 for Chronic Lung Disease. Trends in Pharmacological Sciences 2021;42:354
    https://doi.org/10.1016/j.tips.2021.01.007
  51. Anjali Dhall, Sumeet Patiyal, Neelam Sharma, Naorem Leimarembi Devi, Gajendra.P.S. Raghava. Computer-aided prediction of inhibitors against STAT3 for managing COVID-19 associated cytokine storm. Computers in Biology and Medicine 2021;137:104780
    https://doi.org/10.1016/j.compbiomed.2021.104780
  52. Zhaoyan Lin, Qingqing Li, Ying Zhao, Zixiang Lin, Nan Cheng, Di Zhang, Gang Liu, Jiahao Lin, Hong Zhang, Degui Lin. Combination of Auranofin and ICG-001 Suppress the Proliferation and Metastasis of Colon Cancer. Front. Oncol. 2021;11
    https://doi.org/10.3389/fonc.2021.738085
  53. Hardeep Singh Tuli, Katrin Sak, Ashif Iqubal, Vivek Kumar Garg, Mehmet Varol, Uttam Sharma, Abhishek Chauhan, Mukerrem Betul Yerer, Kuldeep Dhama, Manju Jain, Aklank Jain. STAT signaling as a target for intervention: from cancer inflammation and angiogenesis to non-coding RNAs modulation. Mol Biol Rep 2022;49:8987
    https://doi.org/10.1007/s11033-022-07399-w
  54. Hae Dong Kim, Eun Jung Park, Eun Kyoung Choi, Seuk Young Song, Kwang-Lae Hoe, Dong-Uk Kim. G-749 Promotes Receptor Tyrosine Kinase TYRO3 Degradation and Induces Apoptosis in Both Colon Cancer Cell Lines and Xenograft Mouse Models. Front. Pharmacol. 2021;12
    https://doi.org/10.3389/fphar.2021.730241
  55. Daniel Meraviglia-Crivelli, Helena Villanueva, Angelina Zheleva, María Villalba-Esparza, Beatriz Moreno, Ashwathi Puravankara Menon, Alfonso Calvo, Javier Cebollero, Martin Barainka, Igor Ruiz de los Mozos, Carlos Huesa-Berral, Fernando Pastor. IL-6/STAT3 signaling in tumor cells restricts the expression of frameshift-derived neoantigens by SMG1 induction. Mol Cancer 2022;21
    https://doi.org/10.1186/s12943-022-01679-6
  56. Jianwei Cao, Meiling Liu, Shufang Feng, Yingying Li, Kaijun Zheng. Glaucocalyxin A alleviates lipopolysaccharide‑induced inflammation and apoptosis in pulmonary microvascular endothelial cells and permeability injury by inhibiting STAT3 signaling. Exp Ther Med 2022;23
    https://doi.org/10.3892/etm.2022.11242
  57. Qungang Chang, Detao Yin, Hongqiang Li, Xin Du, Zipeng Wang, Yihao Liu, Jieming Zhang. HDAC6-specific inhibitor alleviates hashimoto's thyroiditis through inhibition of Th17 cell differentiation. Molecular Immunology 2022;149:39
    https://doi.org/10.1016/j.molimm.2022.05.004
  58. Meng Lan, Wenping Lu, Tengteng Zou, Lihong Li, Fengjie Liu, Tiange Cai, Yu Cai. Role of inflammatory microenvironment: potential implications for improved breast cancer nano-targeted therapy. Cell. Mol. Life Sci. 2021;78:2105
    https://doi.org/10.1007/s00018-020-03696-4
  59. Rubia Isler Mancuso, Sara Teresinha Olalla Saad, Juliana Hofstätter Azambuja. Artesunate Switches Monocytes to an Inflammatory Phenotype with the Ability to Kill Leukemic Cells. IJMS 2021;22:608
    https://doi.org/10.3390/ijms22020608
  60. Yinyin Wang, Sihan Liu, Guancheng Jiang, Wanli Zhai, Liu Yang, Mengdi Li, Zhijie Chang, Bingtao Zhu. NOK associates with c-Src and promotes c-Src-induced STAT3 activation and cell proliferation. Cellular Signalling 2020;75:109762
    https://doi.org/10.1016/j.cellsig.2020.109762
  61. Fenghua Liu, Fengyu Qiu, Huayong Chen. miR-124-3p Ameliorates Isoflurane-Induced Learning and Memory Impairment via Targeting STAT3 and Inhibiting Neuroinflammation. Neuroimmunomodulation 2021;28:248
    https://doi.org/10.1159/000515661
  62. Shima Bastaki, Surendar Aravindhan, Nasrin Ahmadpour Saheb, Mahsa Afsari Kashani, Aleksei Evgenievich Dorofeev, Fariba Karoon Kiani, Hediyeh Jahandideh, Farzaneh Beigi Dargani, Mohsen Aksoun, Afshin Nikkhoo, Ali Masjedi, Ata Mahmoodpoor, Majid Ahmadi, Sanam Dolati, Simin Namvar Aghdash, Farhad Jadidi-Niaragh. Codelivery of STAT3 and PD-L1 siRNA by hyaluronate-TAT trimethyl/thiolated chitosan nanoparticles suppresses cancer progression in tumor-bearing mice. Life Sciences 2021;266:118847
    https://doi.org/10.1016/j.lfs.2020.118847
  63. Anna Jaśkiewicz, Tomasz Domoradzki, Beata Pająk. Targeting the JAK2/STAT3 Pathway—Can We Compare It to the Two Faces of the God Janus?. IJMS 2020;21:8261
    https://doi.org/10.3390/ijms21218261
  64. Jeong-Hun Lee, Hwi-Ho Lee, Ki Deok Ryu, Misong Kim, Dohyeong Ko, Kyung-Sook Chung, Ahmed H.E. Hassan, Seung Hyeun Lee, Jae Yeol Lee, Kyung-Tae Lee. KCP10043F Represses the Proliferation of Human Non-Small Cell Lung Cancer Cells by Caspase-Mediated Apoptosis via STAT3 Inactivation. JCM 2020;9:704
    https://doi.org/10.3390/jcm9030704
  65. Ju-Hee Kang, Yeong-Su Jang, Ha Jung Lee, Chang-Yong Lee, Dong Yun Shin, Seung Hyun Oh. Inhibition of STAT3 signaling induces apoptosis and suppresses growth of lung cancer: good and bad. Lab Anim Res 2019;35
    https://doi.org/10.1186/s42826-019-0030-0
  66. James S. Brown. Treatment of cancer with antipsychotic medications: Pushing the boundaries of schizophrenia and cancer. Neuroscience & Biobehavioral Reviews 2022;141:104809
    https://doi.org/10.1016/j.neubiorev.2022.104809
  67. Jiahui Mou, Xiaoding Xu, Feifei Wang, Weiwen Kong, Jing Chen, Jin Ren. HMGN4 plays a key role in STAT3-mediated oncogenesis of triple-negative breast cancer. 2022;43:874
    https://doi.org/10.1093/carcin/bgac056
  68. Luning Li, Cunxin Zhang, Chen Huang, Xinchen Tian, Wenxue Sun, Shulong Jiang, J.B. Heredia. Research Advances in Antitumor Mechanism of Evodiamine. Journal of Chemistry 2022;2022:1
    https://doi.org/10.1155/2022/2784257
  69. Fatema Akhter, Mohammad Saydur Rahman, G M Al Amin, Md. Ibrahim Miah, Young-Sang Koh. Beneficial Therapy with Natural Anti-Inflammatory Agents and Supplements. J Bacteriol Virol. 2021;51:149
    https://doi.org/10.4167/jbv.2021.51.4.149
  70. JaeSang Ko, Ji-Young Kim, Bo Ram Kim, Eun Jig Lee, Don O. Kikkawa, Jin Sook Yoon. Signal transducer and activator of transcription 3 as a potential therapeutic target for Graves’ orbitopathy. Molecular and Cellular Endocrinology 2021;534:111363
    https://doi.org/10.1016/j.mce.2021.111363
  71. Ganggang Mu, Yijie Zhu, Zehua Dong, Lang Shi, Yunchao Deng, Hongyan Li. Calmodulin 2 Facilitates Angiogenesis and Metastasis of Gastric Cancer via STAT3/HIF-1A/VEGF-A Mediated Macrophage Polarization. Front. Oncol. 2021;11
    https://doi.org/10.3389/fonc.2021.727306
  72. Rui-Lin Chen, Zhen Wang, Ping Huang, Cai-Hua Sun, Wen-Ying Yu, Huan-Huan Zhang, Chen-Huan Yu, Jia-Qi He. Isovitexin potentiated the antitumor activity of cisplatin by inhibiting the glucose metabolism of lung cancer cells and reduced cisplatin-induced immunotoxicity in mice. International Immunopharmacology 2021;94:107357
    https://doi.org/10.1016/j.intimp.2020.107357
  73. Francesca Nazio, Agnese Po, Luana Abballe, Claudio Ballabio, Francesca Diomedi Camassei, Matteo Bordi, Antonio Camera, Simona Caruso, Ignazio Caruana, Marco Pezzullo, Caterina Ferraina, Giacomo Milletti, Matteo Gianesello, Sofia Reddel, Carmen Dolores De Luca, Donatella Ceglie, Sara Marinelli, Silvia Campello, Elena Papaleo, Evelina Miele, Antonella Cacchione, Andrea Carai, Maria Vinci, Enrico Velardi, Biagio De Angelis, Luca Tiberi, Concetta Quintarelli, Angela Mastronuzzi, Elisabetta Ferretti, Franco Locatelli, Francesco Cecconi. Targeting cancer stem cells in medulloblastoma by inhibiting AMBRA1 dual function in autophagy and STAT3 signalling. Acta Neuropathol 2021;142:537
    https://doi.org/10.1007/s00401-021-02347-7
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