BMB Reports : eISSN 1976-670X

Cited by CrossRef (174)

  1. Zhipeng Tao, Xu Wu. Transcription Factor Regulatory Networks. .
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  2. M.A.E. Silva, A.L.M. Brand, F.J.M. Novaes, C.M Rezende. Cafestol, Kahweol and Their Acylated Derivatives: Antitumor Potential, Pharmacokinetics, and Chemopreventive Profile. Food Reviews International 2023;39:7048
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  3. Arij Fouzat, Ola Jihad Hussein, Ishita Gupta, Halema F. Al-Farsi, Ashraf Khalil, Ala-Eddin Al Moustafa. Elaeagnus angustifolia Plant Extract Induces Apoptosis via P53 and Signal Transducer and Activator of Transcription 3 Signaling Pathways in Triple-Negative Breast Cancer Cells. Front. Nutr. 2022;9
    https://doi.org/10.3389/fnut.2022.871667
  4. Thu-Huyen Pham, Hyo-Min Park, Jinju Kim, Jin Tae Hong, Do-Young Yoon. STAT3 and p53: Dual Target for Cancer Therapy. Biomedicines 2020;8:637
    https://doi.org/10.3390/biomedicines8120637
  5. Leli Zeng, B. H. Jaswanth Gowda, Mohammed Gulzar Ahmed, Mohammed A. S. Abourehab, Zhe-Sheng Chen, Changhua Zhang, Jia Li, Prashant Kesharwani. Advancements in nanoparticle-based treatment approaches for skin cancer therapy. Mol Cancer 2023;22
    https://doi.org/10.1186/s12943-022-01708-4
  6. Srimathi Devi Jegannathan, Santhosh Arul, Haripriya Dayalan. Zerumbone Sensitizes the Anti-Cancer Efficacy of Cisplatin in Hepatocellular Carcinoma Cells. ACAMC 2022;22:2885
    https://doi.org/10.2174/1871520622666220324090801
  7. Attalla F. El-kott, Eman R. ElBealy, Ali S. Alshehri, Ayman E. El-Kenawy, Heba S. Khalifa, Amira M. AlRamlawy. Salidroside induces cell apoptosis and inhibits the invasiveness of HT29 colorectal cells by regulating protein kinase R, NF-κB and STAT3. CBM 2021;31:13
    https://doi.org/10.3233/CBM-203257
  8. Juan Li, De Bi, Xin Zhang, Yunpeng Cao, Kun Lv, Lan Jiang. Network Pharmacology and Inflammatory Microenvironment Strategy Approach to Finding the Potential Target of Siraitia grosvenorii (Luo Han Guo) for Glioblastoma. Front. Genet. 2021;12
    https://doi.org/10.3389/fgene.2021.799799
  9. Svetlana Gaponova, Olga Patutina, Aleksandra Sen’kova, Ekaterina Burakova, Innokenty Savin, Andrey Markov, Elena Shmendel, Mikhail Maslov, Dmitry Stetsenko, Valentin Vlassov, Marina Zenkova. Single Shot vs. Cocktail: A Comparison of Mono- and Combinative Application of miRNA-Targeted Mesyl Oligonucleotides for Efficient Antitumor Therapy. Cancers 2022;14:4396
    https://doi.org/10.3390/cancers14184396
  10. Mamta Kumari, Praveen Thaggikuppe Krishnamurthy, Piyong Sola. Targeted Drug Therapy to Overcome Chemoresistance in Triple-negative Breast Cancer. CCDT 2020;20:559
    https://doi.org/10.2174/1568009620666200506110850
  11. Radosveta Gencheva, Elias S.J. Arnér. Thioredoxin Reductase Inhibition for Cancer Therapy. Annu. Rev. Pharmacol. Toxicol. 2022;62:177
    https://doi.org/10.1146/annurev-pharmtox-052220-102509
  12. Lei Fan, Jingtao Ru, Tao Liu, Chao Ma. Identification of a Novel Prognostic Gene Signature From the Immune Cell Infiltration Landscape of Osteosarcoma. Front. Cell Dev. Biol. 2021;9
    https://doi.org/10.3389/fcell.2021.718624
  13. Jiantong Hou, Ying Li, Honghong Xing, Ruyu Cao, Xiaomeng Jin, Jing Xu, Yuanqiang Guo. Effusanin B Inhibits Lung Cancer by Prompting Apoptosis and Inhibiting Angiogenesis. Molecules 2023;28:7682
    https://doi.org/10.3390/molecules28237682
  14. Rishav Sharma, Rishabha Malviya. Correlation between hypoxia and HGF/c-MET expression in the management of pancreatic cancer. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 2023;1878:188869
    https://doi.org/10.1016/j.bbcan.2023.188869
  15. Jiao Liu, Kailin Jiao, Qian Zhou, Jun Yang, Keke Yang, Chunyan Hu, Ming Zhou, Zhong Li, Jayeeta Ghose. Resveratrol Alleviates 27-Hydroxycholesterol-Induced Senescence in Nerve Cells and Affects Zebrafish Locomotor Behavior via Activation of SIRT1-Mediated STAT3 Signaling. Oxidative Medicine and Cellular Longevity 2021;2021:1
    https://doi.org/10.1155/2021/6673343
  16. Hyungjin Kim, Hyo-Jung Lee, Deok Yong Sim, Ji Eon Park, Chi-Hoon Ahn, Su-Yeon Park, Eungyeong Jang, Bonglee Kim, Sung-Hoon Kim. The Antitumor Effect of Cinnamaldehyde Derivative CB-PIC in Hepatocellular Carcinoma Cells via Inhibition of Pyruvate and STAT3 Signaling. IJMS 2022;23:6461
    https://doi.org/10.3390/ijms23126461
  17. Li‐Bin Gao, Xin‐Le Zhu, Jing‐Xian Shi, Ling Yang, Zhen‐Qiang Xu, Song‐Lin Shi. HnRNPA2B1 promotes the proliferation of breast cancer MCF‐7 cells via the STAT3 pathway. J of Cellular Biochemistry 2021;122:472
    https://doi.org/10.1002/jcb.29875
  18. Anibal Méndez‑Clemente, Alejandro Bravo‑Cuellar, Salvador González‑Ochoa, Maria Santiago‑Mercado, Luis Palafox‑Mariscal, Luis Jave‑Suárez, Fabiola Solorzano‑Ibarra, Maria Villaseñor‑García, Pablo Ortiz‑Lazareno, Georgina Hernández‑Flores. Dual STAT‑3 and IL‑6R inhibition with stattic and tocilizumab decreases migration, invasion and proliferation of prostate cancer cells by targeting the IL‑6/IL‑6R/STAT‑3 axis. Oncol Rep 2022;48
    https://doi.org/10.3892/or.2022.8349
  19. Zhong Wu, Jin Zhou, Xiaoyang Zhang, Zhouwei Zhang, Yingtian Xie, Jie bin Liu, Zandra V. Ho, Arpit Panda, Xintao Qiu, Paloma Cejas, Israel Cañadas, Fahire Goknur Akarca, James M. McFarland, Ankur K. Nagaraja, Louisa B. Goss, Nikolas Kesten, Longlong Si, Klothilda Lim, Yanli Liu, Yanxi Zhang, Ji Yeon Baek, Yang Liu, Deepa T. Patil, Jonathan P. Katz, Josephine Hai, Chunyang Bao, Matthew Stachler, Jun Qi, Jeffrey J. Ishizuka, Hiroshi Nakagawa, Anil K. Rustgi, Kwok-Kin Wong, Matthew Meyerson, David A. Barbie, Myles Brown, Henry Long, Adam J. Bass. Reprogramming of the esophageal squamous carcinoma epigenome by SOX2 promotes ADAR1 dependence. Nat Genet 2021;53:881
    https://doi.org/10.1038/s41588-021-00859-2
  20. Carole A. Daly, Martine J. Smit, Bianca Plouffe. The constitutive activity of the viral-encoded G protein-coupled receptor US28 supports a complex signalling network contributing to cancer development. 2020;48:1493
    https://doi.org/10.1042/BST20190988
  21. Zuo‐Xin Zhang, Peng Ren, Yong‐Yong Cao, Ting‐Ting Wang, Guo‐Hao Huang, Yao Li, Shuo Zhou, Wei Yang, Lin Yang, Guo‐Long Liu, Yan Xiang, Yu‐Chun Pei, Qiu‐Zi Chen, Ju‐Xiang Chen, Sheng‐Qing Lv. HOXD‐AS2‐STAT3 feedback loop attenuates sensitivity to temozolomide in glioblastoma. CNS Neurosci Ther 2023;29:3430
    https://doi.org/10.1111/cns.14277
  22. Simona Moravcová, Eva Filipovská, Veronika Spišská, Irena Svobodová, Jiří Novotný, Zdeňka Bendová. The Circadian Rhythms of STAT3 in the Rat Pineal Gland and Its Involvement in Arylalkylamine-N-Acetyltransferase Regulation. Life 2021;11:1105
    https://doi.org/10.3390/life11101105
  23. Zeyang Shao, Heng Wang, Haiyan Ren, Yinxiang Sun, Xiuping Chen. The Anticancer Effect of Napabucasin (BBI608), a Natural Naphthoquinone. Molecules 2023;28:5678
    https://doi.org/10.3390/molecules28155678
  24. Nafiseh Behranvand, Farzad Nasri, Reza Zolfaghari Emameh, Pouria Khani, Asieh Hosseini, Johan Garssen, Reza Falak. Chemotherapy: a double-edged sword in cancer treatment. Cancer Immunol Immunother 2022;71:507
    https://doi.org/10.1007/s00262-021-03013-3
  25. Sabrina Giantulli, Elisabetta Tortorella, Francesco Brasili, Susanna Scarpa, Barbara Cerroni, Gaio Paradossi, Angelico Bedini, Stefania Morrone, Ida Silvestri, Fabio Domenici. Effect of 1-MHz ultrasound on the proinflammatory interleukin-6 secretion in human keratinocytes. Sci Rep 2021;11
    https://doi.org/10.1038/s41598-021-98141-2
  26. Chao Wang, Ruijuan Zhang, Xu Chen, Mengyun Yuan, Jian Wu, Qingmin Sun, Chunrun Miao, Yali Jing. The potential effect and mechanism of Saikosaponin A against gastric cancer. BMC Complement Med Ther 2023;23
    https://doi.org/10.1186/s12906-023-04108-3
  27. Salman Ahmed, Hamed Mirzaei, Michael Aschner, Ajmal Khan, Ahmed Al-Harrasi, Haroon Khan. Marine peptides in breast cancer: Therapeutic and mechanistic understanding. Biomedicine & Pharmacotherapy 2021;142:112038
    https://doi.org/10.1016/j.biopha.2021.112038
  28. Cheng Zhang, Shasha Zhao, Huan Deng, Shihua Zhang, Juan Wang, Xiaoye Song, Deen Yu, Yue Zhang, Wensheng Deng. STAT3 promotes RNA polymerase III-directed transcription by controlling the miR-106a-5p/TP73 axis. 2023;12
    https://doi.org/10.7554/eLife.82826
  29. Huanyuan Wang, Dexin Peng, Mei Gan, Zhisheng He, Yukang Kuang. CPEB3 overexpression caused by miR-106b-5p inhibition inhibits esophageal carcinoma in-vitro progression and metastasis. 2022;33:335
    https://doi.org/10.1097/CAD.0000000000001265
  30. In-Hyoung Yang, Seung-Hyun Hong, Minjung Jung, Chi-Hyun Ahn, Hye-Jung Yoon, Seong Doo Hong, Sung-Dae Cho, Ji-Ae Shin. Cryptotanshinone chemosensitivity potentiation by TW-37 in human oral cancer cell lines by targeting STAT3–Mcl-1 signaling. Cancer Cell Int 2020;20
    https://doi.org/10.1186/s12935-020-01495-2
  31. Lei Hua, Yaqing Zhou, Can Hou, Jiaxin Chen, Yanjun Wang, Sheng Zhang, Hanxiao Zhou, Shu He, Enzhi Jia. Shexiang Baoxin Pills Inhibited Proliferation and Migration of Human Coronary Artery Smooth Muscle Cells via PI3K/AKT/mTOR Pathway. Front. Cardiovasc. Med. 2021;8
    https://doi.org/10.3389/fcvm.2021.700630
  32. Fengjie Wan, Hui Li, Shiping Huang, Junming Sun, Jiafu Li, Yasi Li, Lichao Yang, Min He. Vasorin promotes proliferation and migration via STAT3 signaling and acts as a promising therapeutic target of hepatocellular carcinoma. Cellular Signalling 2023;110:110809
    https://doi.org/10.1016/j.cellsig.2023.110809
  33. Nan Huang, Qichang Xing, Wencan Li, Qingzi Yan, Renzhu Liu, Xiang Liu, Zheng Liu. Explore the mechanism of ursolic acid acting on atherosclerosis through network pharmacological and bioinformatics methods. 2023;102:e34362
    https://doi.org/10.1097/MD.0000000000034362
  34. Manal Alfwuaires, Hany Elsawy, Azza Sedky. Acacetin Inhibits Cell Proliferation and Induces Apoptosis in Human Hepatocellular Carcinoma Cell Lines. Molecules 2022;27:5361
    https://doi.org/10.3390/molecules27175361
  35. Melani Luque, Marta Sanz-Álvarez, Andrea Santamaría, Sandra Zazo, Ion Cristóbal, Lorena de la Fuente, Pablo Mínguez, Pilar Eroles, Ana Rovira, Joan Albanell, Juan Madoz-Gúrpide, Federico Rojo. Targeted Therapy Modulates the Secretome of Cancer-Associated Fibroblasts to Induce Resistance in HER2-Positive Breast Cancer. IJMS 2021;22:13297
    https://doi.org/10.3390/ijms222413297
  36. Zhen-Duo Shi, Kun Pang, Zhuo-Xun Wu, Yang Dong, Lin Hao, Jia-Xin Qin, Wei Wang, Zhe-Sheng Chen, Cong-Hui Han. Tumor cell plasticity in targeted therapy-induced resistance: mechanisms and new strategies. Sig Transduct Target Ther 2023;8
    https://doi.org/10.1038/s41392-023-01383-x
  37. Daoyuan Chen, Xuecun Liu, Xiaoyan Lu, Jingwei Tian. Nanoparticle drug delivery systems for synergistic delivery of tumor therapy. Front. Pharmacol. 2023;14
    https://doi.org/10.3389/fphar.2023.1111991
  38. B. F. Yan, X. Chen, J. Liu, S. J. Liu, J. Z. Zhang, Qingqi Zeng, J. A. Duan. Asiatic Acid Induces Mitochondrial Apoptosis via Inhibition of JAK2/STAT3 Signalling Pathway in Human Osteosarcoma. Fol. Biol. 2021;67:108
    https://doi.org/10.14712/fb2021067030108
  39. Ming Shen, Yan-jun Wang, Zhao-hua Liu, Yan-wen Chen, Qian-kun Liang, Yang Li, Hai-xia Ming, San Jun Shi. Inhibitory Effect of Astragalus Polysaccharide on Premetastatic Niche of Lung Cancer through the S1PR1-STAT3 Signaling Pathway. Evidence-Based Complementary and Alternative Medicine 2023;2023:1
    https://doi.org/10.1155/2023/4010797
  40. Hsueh-Yao Chu, Yin-Ju Chen, Chun-Jieh Hsu, Yang-Wei Liu, Jeng-Fong Chiou, Long-Sheng Lu, Fan-Gang Tseng. Physical Cues in the Microenvironment Regulate Stemness-Dependent Homing of Breast Cancer Cells. Cancers 2020;12:2176
    https://doi.org/10.3390/cancers12082176
  41. Stefano Comità, Saveria Femmino, Cecilia Thairi, Giuseppe Alloatti, Kerstin Boengler, Pasquale Pagliaro, Claudia Penna. Regulation of STAT3 and its role in cardioprotection by conditioning: focus on non-genomic roles targeting mitochondrial function. Basic Res Cardiol 2021;116
    https://doi.org/10.1007/s00395-021-00898-0
  42. Sung-Jun Hong, Jin-Tae Kim, Su-Jung Kim, Nam-Chul Cho, Kyeojin Kim, Seungbeom Lee, Young-Ger Suh, Kyung-Cho Cho, Kwang Pyo Kim, Young-Joon Surh. An Electrophilic Deguelin Analogue Inhibits STAT3 Signaling in H-Ras-Transformed Human Mammary Epithelial Cells: The Cysteine 259 Residue as a Potential Target. Biomedicines 2020;8:407
    https://doi.org/10.3390/biomedicines8100407
  43. Chien-Chi Lu, Hsiao-Chi Tsai, Dong-Ying Yang, Shih-Wei Wang, Ming-Hsui Tsai, Chun-Hung Hua, Kwei-Jing Chen, Michael Yuan-Chien Chen, Ming-Yu Lien, Chih-Hsin Tang. The Chemokine CCL4 Stimulates Angiopoietin-2 Expression and Angiogenesis via the MEK/ERK/STAT3 Pathway in Oral Squamous Cell Carcinoma. Biomedicines 2022;10:1612
    https://doi.org/10.3390/biomedicines10071612
  44. Sultana Mehbuba Hossain, Michael R. Eccles. Phenotype Switching and the Melanoma Microenvironment; Impact on Immunotherapy and Drug Resistance. IJMS 2023;24:1601
    https://doi.org/10.3390/ijms24021601
  45. Junbiao Wang, Romilde Iannarelli, Stefania Pucciarelli, Emiliano Laudadio, Roberta Galeazzi, Mara Giangrossi, Maurizio Falconi, Lishan Cui, Aleix Marti Navia, Michela Buccioni, Gabriella Marucci, Daniele Tomassoni, Laura Serini, Stefania Sut, Filippo Maggi, Stefano Dall’Acqua, Cristina Marchini, Augusto Amici. Acetylshikonin isolated from Lithospermum erythrorhizon roots inhibits dihydrofolate reductase and hampers autochthonous mammary carcinogenesis in Δ16HER2 transgenic mice. Pharmacological Research 2020;161:105123
    https://doi.org/10.1016/j.phrs.2020.105123
  46. Mohammad Dabaghi, Seyed Mohammad Mahdi Rasa, Emilio Cirri, Alessandro Ori, Francesco Neri, Rainer Quaas, Ingrid Hilger. Iron Oxide Nanoparticles Carrying 5-Fluorouracil in Combination with Magnetic Hyperthermia Induce Thrombogenic Collagen Fibers, Cellular Stress, and Immune Responses in Heterotopic Human Colon Cancer in Mice. Pharmaceutics 2021;13:1625
    https://doi.org/10.3390/pharmaceutics13101625
  47. Chen Chang, Ruping Cai, Qiang Wu, Qiang Su. Uncovering the Genetic Link between Acute Myocardial Infarction and Ulcerative Colitis Co-Morbidity through a Systems Biology Approach. CVIA 2023;8
    https://doi.org/10.15212/CVIA.2023.0034
  48. Ngoc Bao To, Yen Thi-Kim Nguyen, Jeong Yong Moon, Meran Keshawa Ediriweera, Somi Kim Cho. Pentadecanoic Acid, an Odd-Chain Fatty Acid, Suppresses the Stemness of MCF-7/SC Human Breast Cancer Stem-Like Cells through JAK2/STAT3 Signaling. Nutrients 2020;12:1663
    https://doi.org/10.3390/nu12061663
  49. Israa A. Cheikh, Chirine El-Baba, Ali Youssef, Najat A. Saliba, Akram Ghantous, Nadine Darwiche. Lessons learned from the discovery and development of the sesquiterpene lactones in cancer therapy and prevention. Expert Opinion on Drug Discovery 2022;17:1377
    https://doi.org/10.1080/17460441.2023.2147920
  50. Wenbo Shao, Cunxin Zhang, Kang Li, Ziang Lu, Zihao Zhao, Kai Gao, Chaoliang Lv. Wogonin Inhibits Inflammation and Apoptosis Through STAT3 Signal Pathway to Promote the Recovery of Spinal Cord Injury. SSRN Journal 2021
    https://doi.org/10.2139/ssrn.3996831
  51. Christian A. Maino Vieytes, Laura S. Rozek, Gregory T. Wolf, Anna E. Arthur. Associations Between Diet Quality and Proinflammatory Cytokines in Newly Diagnosed Head and Neck Cancer Survivors. Current Developments in Nutrition 2023;7:102015
    https://doi.org/10.1016/j.cdnut.2023.102015
  52. Haosheng Ni, Hui Sun, Miaosen Zheng, Tingting Bian, Jian Liu, Xiaoli Li, Jianguo Zhang, Yifei Liu. Mining database for the expression and clinical significance of STAT family in head and neck squamous cell carcinomas. Translational Oncology 2021;14:100976
    https://doi.org/10.1016/j.tranon.2020.100976
  53. Laura Magnano, Andrea Rivero, Estella Matutes. Large Granular Lymphocytic Leukemia: Current State of Diagnosis, Pathogenesis and Treatment. Curr Oncol Rep 2022;24:633
    https://doi.org/10.1007/s11912-021-01159-y
  54. Jin Li, Zi-Hui Wang, Ya-Min Dang, Dan-Ni Li, Zhen Liu, Da-Peng Dai, Jian-Ping Cai. MTH1 suppression enhances the stemness of MCF7 through upregulation of STAT3. Free Radical Biology and Medicine 2022;188:447
    https://doi.org/10.1016/j.freeradbiomed.2022.06.240
  55. Salman Ahmed, Waqas Alam, Michael Aschner, Rosanna Filosa, Wai San Cheang, Philippe Jeandet, Luciano Saso, Haroon Khan. Marine Cyanobacterial Peptides in Neuroblastoma: Search for Better Therapeutic Options. Cancers 2023;15:2515
    https://doi.org/10.3390/cancers15092515
  56. Mingzhu Li, Lina Duan, Wenjie Wu, Wenjing Li, Lili Zhao, Ang Li, Xuebo Lu, Xinyu He, Zigang Dong, Kangdong Liu, Yanan Jiang. Vortioxetine hydrobromide inhibits the growth of gastric cancer cells in vivo and in vitro by targeting JAK2 and SRC. Oncogenesis 2023;12
    https://doi.org/10.1038/s41389-023-00472-4
  57. Fanglin Niu, Yi Yu, Zhuozhuo Li, Yuanyuan Ren, Zi Li, Qiang Ye, Ping Liu, Chenshuang Ji, Lu Qian, Yuyan Xiong. Arginase: An emerging and promising therapeutic target for cancer treatment. Biomedicine & Pharmacotherapy 2022;149:112840
    https://doi.org/10.1016/j.biopha.2022.112840
  58. Shokoofe Noori, Mitra Nourbakhsh, Shabnam Farzaneh, Afshin Zarghi. A Ferrocene Derivative Reduces Cisplatin Resistance in Breast Cancer Cells through Suppression of MDR-1 Expression and Modulation of JAK2/STAT3 Signaling Pathway. ACAMC 2020;20:2285
    https://doi.org/10.2174/1871520620666200807103903
  59. Shu Dai, Cheng Wang, XingTao Zhao, Cheng Ma, Ke Fu, Yanfang Liu, Cheng Peng, Yunxia Li. Cucurbitacin B: A review of its pharmacology, toxicity, and pharmacokinetics. Pharmacological Research 2023;187:106587
    https://doi.org/10.1016/j.phrs.2022.106587
  60. Sergei S. Naumov, Denis E. Kulbakin, Nadezhda V. Krakhmal, Sergey V. Vtorushin. Molecular and biological factors in the prognosis of head and neck squamous cell cancer. Mol Biol Rep 2023;50:7839
    https://doi.org/10.1007/s11033-023-08611-1
  61. Lara J. Bou Malhab, Wael M. Abdel-Rahman. Obesity and Inflammation: Colorectal Cancer Engines. CMP 2022;15:620
    https://doi.org/10.2174/1874467214666210906122054
  62. Dong Hyun Jo, Seungbeom Lee, Eunoo Bak, Chang Sik Cho, Young Taek Han, Kyeojin Kim, Young-Ger Suh, Jeong Hun Kim. Antitumor Activity of Novel Signal Transducer and Activator of Transcription 3 Inhibitors on Retinoblastoma. Mol Pharmacol 2021;100:63
    https://doi.org/10.1124/molpharm.120.000231
  63. Wenbo Shao, Cunxin Zhang, Kang Li, Ziang Lu, Zihao Zhao, Kai Gao, Chaoliang Lv. Wogonin inhibits inflammation and apoptosis through STAT3 signal pathway to promote the recovery of spinal cord injury. Brain Research 2022;1782:147843
    https://doi.org/10.1016/j.brainres.2022.147843
  64. Shiqi Kong, Xinbo Ge, Xin Li, Zhenbo Liu, Rui Zhang, Ming Yang, Zhenhai Wang, Zhenzhong Li. SD‐36 promotes growth inhibition and induces apoptosis via suppression of Mcl‐1 in glioma. J Cellular Molecular Medi 2021;25:8261
    https://doi.org/10.1111/jcmm.16754
  65. Byung-Hak Kim, Haeri Lee, Cheol Gyu Park, Ae Jin Jeong, Song-Hee Lee, Kum Hee Noh, Jong Bae Park, Chung-Gi Lee, Sun Ha Paek, Hyunggee Kim, Sang-Kyu Ye. STAT3 Inhibitor ODZ10117 Suppresses Glioblastoma Malignancy and Prolongs Survival in a Glioblastoma Xenograft Model. Cells 2020;9:722
    https://doi.org/10.3390/cells9030722
  66. Andarz Fazlollahpour Naghibi, Danyal Daneshdoust, Seyed Reza Taha, Sara Abedi, Pardis Abdali Dehdezi, Mahdieh Shariat Zadeh, Fatemeh Dokoohaki, Mehdi Soleymani-Goloujeh. Role of cancer stem cell-derived extracellular vesicles in cancer progression and metastasis. Pathology - Research and Practice 2023;247:154558
    https://doi.org/10.1016/j.prp.2023.154558
  67. Josephine Hendrikson, Ying Liu, Wai Har Ng, Jing Yi Lee, Abner Herbert Lim, Jui Wan Loh, Cedric C.Y. Ng, Whee Sze Ong, Joey Wee-Shan Tan, Qiu Xuan Tan, Gillian Ng, Nicholas B. Shannon, Weng Khong Lim, Tony K.H. Lim, Clarinda Chua, Jolene Si Min Wong, Grace Hwei Ching Tan, Jimmy Bok Yan So, Khay Guan Yeoh, Bin Tean Teh, Claramae Shulyn Chia, Khee Chee Soo, Oi Lian Kon, Iain Beehuat Tan, Jason Yongsheng Chan, Melissa Ching Ching Teo, Chin-Ann J. Ong. Ligand-mediated PAI-1 inhibition in a mouse model of peritoneal carcinomatosis. Cell Reports Medicine 2022;3:100526
    https://doi.org/10.1016/j.xcrm.2022.100526
  68. Kyle A. Rohrer, Heyu Song, Anum Akbar, Yingling Chen, Suravi Pramanik, Phillip J. Wilder, Erin M. McIntyre, Nagendra K. Chaturvedi, Kishor K. Bhakat, Angie Rizzino, Don W. Coulter, Sutapa Ray. STAT3 Inhibition Attenuates MYC Expression by Modulating Co-Activator Recruitment and Suppresses Medulloblastoma Tumor Growth by Augmenting Cisplatin Efficacy In Vivo. Cancers 2023;15:2239
    https://doi.org/10.3390/cancers15082239
  69. Jialei Yang, Wanting He, Lian Gu, Lulu Zhu, Tian Liang, Xueying Liang, Qingqing Zhong, Ruirui Zhang, Aruo Nan, Li Su. CircFOXP1 alleviates brain injury after acute ischemic stroke by regulating STAT3/apoptotic signaling. Translational Research 2023;257:15
    https://doi.org/10.1016/j.trsl.2023.01.007
  70. Banumathi, Ankith Sherapura, Vikas H. Malojirao, Zabiulla, B. S. Sharath, Prabhu Thirusangu, Riaz Mahmood, N. Suchetha Kumari, Shrinath M. Baliga, Shaukath Ara Khanum, B. T. Prabhakar. Antiproliferative pharmacophore azo-hydrazone analogue BT-1F exerts death signalling pathway targeting STAT3 in solid tumour. Pharmacol. Rep 2022;74:353
    https://doi.org/10.1007/s43440-021-00345-w
  71. Joaquín Martínez‑López, Pau Montesinos, Nieves López‑Muñoz, Rosa Ayala, Pilar Martínez‑Sánchez, Julian Gorrochategui, José Rojas‑Rudilla, Daniel Primo, Juan-Miguel Bergua‑Burgues, María Calbacho, Evelyn Acuña‑Cruz, José Pérez‑Simón, Adolfo De La Fuente, Jaime Pérez De Oteyza, Rebeca Rodriguez‑Veiga, José Pina, Blanca Boluda, Isabel Cano, María Paciello Coronel, Juan Ballesteros. Biomarker‑driven phase Ib clinical trial of OPB‑111077 in acute myeloid leukemia. Med Int 2022;2
    https://doi.org/10.3892/mi.2022.32
  72. Dongdong Huang, Rui Lu, Mingjing Cai, Jie Meng, Shuangba He, Qingxiang Zhang, Wei Meng. Effects of Arctigenin in Proliferation, Migration, and Invasion of Nasopharyngeal Carcinoma 5-8F Cells. ACAMC 2023;23:1211
    https://doi.org/10.2174/1871520623666230228155129
  73. Chun-Yan Li, Chun-Ya Chen, Jian-Hong An, Jian-Bin Wu, Hong Shen. Normal Basal Epithelial Cells Stimulate the Migration and Invasion of Prostate Cancer Cell RM-1 by TGF-β1/STAT3 Axis in vitro. CMAR 2021;Volume 13:3685
    https://doi.org/10.2147/CMAR.S303122
  74. Rosa K. Kortekaas, Janette K. Burgess, Roël van Orsoy, David Lamb, Megan Webster, Reinoud Gosens. Therapeutic Targeting of IL-11 for Chronic Lung Disease. Trends in Pharmacological Sciences 2021;42:354
    https://doi.org/10.1016/j.tips.2021.01.007
  75. Anjali Dhall, Sumeet Patiyal, Neelam Sharma, Naorem Leimarembi Devi, Gajendra.P.S. Raghava. Computer-aided prediction of inhibitors against STAT3 for managing COVID-19 associated cytokine storm. Computers in Biology and Medicine 2021;137:104780
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