• Mitochondrial noncoding RNA transport

    Fig. 1. Schematic of the ncRNAs transported through the mitochondrial outer and inner membranes (OM, IM). Left, ncRNAs synthesized in mitochondria but found elsewhere (nucleus and extracellular space); right, ncRNAs synthesized in the nucleus and found in mitochondria, including tRNAs, 5S rRNA, lncRNAs like RMRP, and microRNAs and their precursors. Transport factors identified as mediators of these processes, including many ncRNA-interacting RBPs, are indicated. Yellow, nucleus; gray, cytoplasm; blue, mitochondria; pink, extracellular space.
  • Nonsense-mediated mRNA decay at the crossroads of many cellular pathways

    Fig. 2. NMD interacts with cellular processes in different ways: (i) bidirectional interactions in which NMD and a cellular process influence each other (bidirectional arrows); (ii) unidirectional interactions in which NMD influences a cellular process (arrows pointing a cellular process); (iii) unidirectional interactions in which a cellular process regulates NMD efficiency (arrows pointing NMD).
  • Translation initiation mediated by nuclear cap-binding protein complex

    Fig. 3. Translational control under prolonged hypoxic conditions. The details are described in the text.
  • Translational control of mRNAs by 3’-Untranslated region binding proteins

    Fig. 1. mRNA processing generates 3’-UTR variants. (A) Schematic depictions of pre-mRNA and mature mRNA. UTR (untranslated region), CDS (protein coding sequence), UC-PAS (upstream core polyadenylation signal), DC-PAS (downstream core polyadenylation signal). (B) mRNA isoforms with alternative poly(A) additions.

BMB Reports 2017; 50(4): 157~231
Editorial
RNA at the heart of gene expression: Special issue of BMB Reports 2017
Yoon Ki Kim
BMB Reports 2017; 50(4): 157-157  
Perspectives
Non-canonical targets play an important role in microRNA stability control mechanisms
June Hyun Park & Chanseok Shin,*
BMB Reports 2017; 50(4): 158-159  
Longevity regulation by NMD-mediated mRNA quality control
Heehwa G. Son & Seung-Jae V. Lee,*
BMB Reports 2017; 50(4): 160-161  
Fine-tuning of gene expression dynamics by the Set2-Rpd3S pathway
Bo Bae Lee#, Ji Hyun Kim# & TaeSoo Kim*
BMB Reports 2017; 50(4): 162-163  
Invited Mini Reviews
Mitochondrial noncoding RNA transport
Kyoung Mi Kim, Ji Heon Noh*, Kotb Abdelmohsen & Myriam Gorospe
BMB Reports 2017; 50(4): 164-174  
Nonsense-mediated mRNA decay at the crossroads of many cellular pathways
Fabrice Lejeune
BMB Reports 2017; 50(4): 175-185  
Translation initiation mediated by nuclear cap-binding protein complex
Incheol Ryu & Yoon Ki Kim
BMB Reports 2017; 50(4): 186-193  
Translational control of mRNAs by 3’-Untranslated region binding proteins
Akio Yamashita & Osamu Takeuchi
BMB Reports 2017; 50(4): 194-200  
Analyses of alternative polyadenylation: from old school biochemistry to high-throughput technologies
Hsin-Sung Yeh, Wei Zhang & Jeongsik Yong
BMB Reports 2017; 50(4): 201-207  
Articles
miR-374 promotes myocardial hypertrophy by negatively regulating vascular endothelial growth factor receptor-1 signaling
Jong Sub Lee, Dong Woo Song, Jei Hyoung Park, Jin Ock Kim, Chunghee Cho & Do Han Kim*
BMB Reports 2017; 50(4): 208-213  
microRNA-200a-3p enhances mitochondrial elongation by targeting mitochondrial fission factor
Heejin Lee, Hyosun Tak, So Jung Park, Yoon Kyung Jo, Dong Hyung Cho,* & Eun Kyung Lee
BMB Reports 2017; 50(4): 214-219  
hnRNPK-regulated PTOV1-AS1 modulates heme oxygenase-1 expression via miR-1207-5p
Chang Hoon Shin, Seongho Ryu & Hyeon Ho Kim
BMB Reports 2017; 50(4): 220-225  
Post-transcriptional and translational regulation of mRNA-like long non-coding RNAs by microRNAs in early developmental stages of zebrafish embryos
Kyung-Tae Lee & Jin-Wu Nam
BMB Reports 2017; 50(4): 226-231  

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April 2017
Volume 50
Issue 4

2015 SCI Impact Factor 2.782

BIOCHEMISTRY & MOLECULAR BIOLOGY 138/289

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