• Role of the CCN protein family in cancer

    Fig. 1. Structure and nomenclature of CCN protein family members. (Left) The amino acid location of the four conserved motifs (IGFBP, VWC, TSR, and CT) are represented as Arabic numerals. (Right) Alternative names for the CCN proteins are indicated. Abbreviations: Cyr61, cysteine rich 61; CTGF-2, connective tissue growth factor 2; IGFBP10, insulin-like growth factor-binding protein 10; IGFBP-rP4, IGFBP-related protein 4; HBGF-0.8, heparin-binding growth factor 0.8; HCS24, hypertrophic chondrocyte specific 24; NOV, nephroblastoma overexpressed gene; NOVH, human nov gene; Wisp, Wnt-inducible secreted protein; Elm-1, expressed in low metastatic cells; HICP, heparin-induced CCN-like protein; and Cop-1, card-only protein 1.
  • MicroRNA controls of cellular senescence

    Fig. 1. miRNAs regulate key signaling pathways critical for cellular senescence.
  • Investigating the role of Sirtuins in cell reprogramming

    Fig. 1. The function of sirtuins on genome stability. Sirt 1, 2, and 6 control the chromatin state by regulating the activation of enzymes during chromatic remodeling. Sirt1 removes acetylates in Sox2 and Myc removes methylates in Oct4. Also, Sirt2 modulates the stability of the Myc protein. SIRT6 can deacetylate H3K9Ac and H3K56Ac and is involved in the transcription of c- Myc. AC: Acetylation, ME: Methylation, SIRT: Surtuin.

BMB Reports 2018; 51(10): 481~543
The origin-of-cell harboring cancer-driving mutations in human glioblastoma
Joo Ho Lee, Jeong Ho Lee
BMB Reports 2018; 51(10): 481-483  https://doi.org/10.5483/BMBRep.2018.51.10.233
Regulation of RIP3 protein stability by PELI1-mediated proteasome-dependent degradation
Han-Hee Park, Michael J. Morgan, Ho Chul Kang and You-Sun Kim
BMB Reports 2018; 51(10): 484-485  https://doi.org/10.5483/BMBRep.2018.51.10.217
Invited Mini Reviews
Role of the CCN protein family in cancer
Hyungjoo Kim, Seogho Son and Incheol Shin
BMB Reports 2018; 51(10): 486-492  https://doi.org/10.5483/BMBRep.2018.51.10.192
MicroRNA controls of cellular senescence
Nayoung Suh*
BMB Reports 2018; 51(10): 493-499  https://doi.org/10.5483/BMBRep.2018.51.10.209
Investigating the role of Sirtuins in cell reprogramming
Jaein Shin, Junyeop Kim, Hanseul Park and Jongpil Kim
BMB Reports 2018; 51(10): 500-507  https://doi.org/10.5483/BMBRep.2018.51.10.172
29-kDa FN-f inhibited autophagy through modulating localization of HMGB1 in human articular chondrocytes
Hyun Sook Hwang, Min Ha Choi and Hyun Ah Kim
BMB Reports 2018; 51(10): 508-513  https://doi.org/10.5483/BMBRep.2018.51.10.058
TRRAP stimulates the tumorigenic potential of ovarian cancer stem cells
Kyung Taek Kang, Yang Woo Kwon, Dae Kyoung Kim, Su In Lee, Ki-Hyung Kim, Dong-Soo Suh and Jae Ho Kim
BMB Reports 2018; 51(10): 514-519  https://doi.org/10.5483/BMBRep.2018.51.10.042
LJ-1888, a selective antagonist for the A3 adenosine receptor, ameliorates the development of atherosclerosis and hypercholesterolemia in apolipoprotein E knock-out mice
Jong-Gil Park, Se-Jin Jeong, Jinha Yu, Gyudong Kim, Lak Shin Jeong and Goo Taeg Oh
BMB Reports 2018; 51(10): 520-525  https://doi.org/10.5483/BMBRep.2018.51.10.098
Facile analysis of protein-protein interactions in living cells by enriched visualization of the p-body
Miri Choi, Jiyeon Baek, Sang-Bae Han and Sungchan Cho
BMB Reports 2018; 51(10): 526-531  https://doi.org/10.5483/BMBRep.2018.51.10.051
Cordycepin inhibits lipopolysaccharide-induced cell migration and invasion in human colorectal carcinoma HCT-116 cells through down-regulation of prostaglandin E2 receptor EP4
Jin-Woo Jeong, Cheol Park, Hee-Jae Cha, Su Hyun Hong, Shin-Hyung Park, Gi-Young Kim, Woo Jean Kim, Cheol Hong Kim, Kyoung Seob Song and Yung Hyun Choi
BMB Reports 2018; 51(10): 532-537  https://doi.org/10.5483/BMBRep.2018.51.10.120
PEP-1-paraoxonase 1 fusion protein prevents cytokine-induced cell destruction and impaired insulin secretion in rat insulinoma cells
Su Jin Lee, Hyung Kyung Kang, Yeon Joo Choi, Won Sik Eum, Jinseu Park, Soo Young Choi and Hyeok Yil Kwon
BMB Reports 2018; 51(10): 538-543  https://doi.org/10.5483/BMBRep.2018.51.10.181


Current Issue

October 2018
Volume 51
Issue 10

2017 SCI Impact Factor 3.085


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