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Fig. 2.

ACOX1 modulates doxorubicin-induced cytotoxic effect. (A, B) ACOX1 expressed Raji cells and control cells (Con.) were treated with doxorubicin (0.6 μM) or control solvent for 48 hours. Cells were subjected to apoptosis analysis (A). Statistical results are shown (B). (C, D) shACOX1 expressed Raji cells and control cells (NC) were treated with doxorubicin (0.1 μM) or control solvent for 48 hours. Cells were subjected to apoptosis analysis (C). Statistical results are shown (D). (E, F) Treatment was the same as (A) and (B). Cells were subjected to TUNEL assay analysis (E). Statistical results are shown (F). (G, H) Treatment was the same as (C) and (D). Cells were subjected to TUNEL assay analysis (G). Statistical results are shown (H). The bar represents mean ± SD of three independent experiments (*P < 0.05, **P < 0.01, ***P < 0.001, The ANOVA test, followed by Least Significant Difference test, were used to make statistical comparisons).

BMB Reports 2019;52:566~571 https://doi.org/10.5483/BMBRep.2019.52.9.094
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