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Fig. 1. Biological functions of IL-32 in inflammatory tumors. Different colors indicate each cancer type and cancer type specific signaling pathway. AOM: azoxymethane, ROS: reactive oxygen species, JNK: c-Jun N-terminal kinases, NF-κB: nuclear factor kappa B, TIMP: tissue inhibitors of metalloproteinase, MMP: matrix metalloproteinase, H. pylori: Helicobacter pylori, cagPAI: cytotoxin-associated gene pathogenicity island, HBV: hepatitis B virus, HCV: hepatitis C virus, VEGF: vascular endothelial growth factor, CXCL: C-X-C motif chemokine, CCL: C-C motif chemokine ligands, TNF-α: tumor necrosis factor α, PI3K: phosphoinositide 3-kinase, AP-1: activated protein 1.
BMB Reports 2019;52:165~174 https://doi.org/10.5483/BMBRep.2019.52.3.019
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