BMB Reports : eISSN 1976-670X

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Fig. 1. Age-related autophagy and muscle degeneration in skeletal muscle. Autophagy normally functions as a physiological process to degrade cytoplasmic aggregates, or organelles. Aging in skeletal muscle can result in an imbalance of muscle mass and strength. Not only autophagy defect is closely linked to the loss of muscle in aging, but muscle degeneration with aging results from decreases in both number and size of muscle fibers.
BMB Reports 2019;52:64~69
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