BMB Reports : eISSN 1976-670X

Download original image
Fig. 1. Excitatory motor signals in the thalamus generate multiple PD-like motor symptoms. In low dopamine condition, enhanced basal ganglia inputs to the thalamus generate rebound firing (rebound excitation) in many thalamic neurons. Suppression of rebound firing by CaV3.1 KO or direct inhibition of thalamic activity rescue PD-like motor problems.
BMB Reports 2018;51:3~4
© BMB Rep.